• !Break The Internet Tomorrow
    Tomorrow, I am going to take AVC offline to show the FCC what the Internet will look like if they repeal the Net Neutrality rules. It is part of a collective action called Break The Internet. If you want to join me in this protest, you can get what y…
    - 11 hours ago 11 Dec 17, 11:12am -
  • Proceed With Caution
    The CEO of Coinbase, a company that I am on the Board of, wrote a note to all of their customers on Friday. That note, which he also posted to his blog,  urged caution in the trading of crypto assets such as Bitcoin and Ethereum. This is a quote fro…
    - 1 day ago 10 Dec 17, 2:00pm -
  • Video Of The Week: Samir Desai at Slush
    One of the most impressive startup executions I have witnessed in the past ten years is what the team at Funding Circle has pulled off. They have gone from a team of friends with an idea to the largest non bank lender in the western world. In this in…
    - 2 days ago 9 Dec 17, 1:44pm -
  • Funding Friday: Brooklyn Cider House
    I backed this project today. The idea of a cider bar and restaurant in Bushwick seems so right to me. There is less than 24 hours left on this project. I’m hoping we can help them get across the finish line.
    - 3 days ago 8 Dec 17, 11:27am -
  • CS Education Week In NYC
    All over the city this week, students in NYC’s public schools have been celebrating CS Education Week by doing events and hackathons to showcase their coding skills. Through NYC’s CS4All program, over 1000 teachers have been trained to teach CS c…
    - 4 days ago 7 Dec 17, 3:19pm -

Both Sides of The Table

  • Why We Must Have Zero Tolerance for Sexual Misconduct (Venture Capital Edition)
    Time Magazine published its “person of the year” edition today and honored “the silence breakers” for speaking up and forcing our society to confront its position towards men in power exploiting their power for sexual gain. Real change is cle…
    - 4 days ago 8 Dec 17, 12:30am -
  • What Happens When Startups Turn from Their Innovation Stage to Operational Excellence?
    Nearly every successful tech startup I’ve observed over the past 20 years has gone through a similar growth pattern: Innovate, systematize then scale operations.An alternate outcome that I also unfortunately observe in some cases are companies who…
    - 27 days ago 14 Nov 17, 9:09pm -
  • One Small Change I Made That Improved My Daily Mental State
    We all have a pretty good idea about things that drag down our productivity or suck up time that would be better spent on more fulfilling activities.Two years ago I made a commitment to stop bringing my mobile phone into my bedroom and with like a 95…
    - 49 days ago 24 Oct 17, 5:45am -
  • Why the Former President of Nickelodeon Joined mitú as CEO.
    Why the Former President of Nickelodeon Joined mitú as CEO. (Hint: 60 million US Latinos driving US growth engine)I am beyond excited to announce the Herb Scannell has agreed to move from NYC to Los Angeles to take on the role of CEO at mitú, the…
    - 83 days ago 19 Sep 17, 7:45pm -
  • Want to Really Understand What all the Hype of Cryptocurrency is About?
    If you read the headlines you may well think cryptocurrencies are a either a radically new way of paying that is our savior from ossified, corrupt governments or on the other side that they are speculative Ponzi schemes. The reality of course is that…
    - 84 days ago 18 Sep 17, 3:44pm -

Tomasz Tunguz

  • Premoney vs Postmoney - Which is a Better Technique for Negotiating?
    When negotiating your next fundraising round, should you talk valuation in premoney terms or postmoney terms? Premoney is the valuation before the investment, employee stock option pool (ESOP) expansion, debt-to-equity conversion and investment. Po…
    - 2 days ago 10 Dec 17, 12:00am -
  • Meetings Shouldn't Be Boring
    A friend suggested that I read the Five Dysfunctions of a Team over the weekend. Though I’m passionate about business books, I rolled my eyes. I had seen this one on best seller lists for a long time, and never thought it would have much to offer…
    - 9 days ago 3 Dec 17, 12:00am -
  • Managers Must be Insane to Brainstorm in Groups
    “Evidence from science suggests that business people must be insane to use brainstorming groups.” That’s a shocking statement. Adrian Furnham, a professor of organizational and applied psychology at University College London, said it. It turn…
    - 12 days ago 30 Nov 17, 12:00am -
  • How Quickly Does Headcount Scale in the Fastest Growing Software Businesses?
    How quickly do the fastest growing software companies build their teams? The answer is incredibly quickly. In fact, this data bolsters the notion that management team’s top priority is recruiting, especially after the business has reached product…
    - 13 days ago 29 Nov 17, 12:00am -
  • The Parallel Between Cryptocurrency and Continentals
    There’s a parallel between cryptoassets today and the British colonial period predating the US. In the late-1600s, colonies began to print their own money. Today, we’re seeing many startups coin their own money, creating an explosion in the num…
    - 16 days ago 26 Nov 17, 12:00am -

Semil Shah

  • The Breakout Tech Company Of 2017

    - 6 days ago 6 Dec 17, 7:14am -
  • The Story Behind My Investment In Perlara
    Almost two years ago, I met a founding team during Y Combinator batch. It was in a field I haven’t invested in before, but I have spent time in during a previous life and career. We met for coffee on the Embarcadero, and while my “life sciences l…
    - 36 days ago 5 Nov 17, 10:36pm -
  • The Story Behind My Investment In Optimus Ride
    About a year ago, thanks to an investor friend who, in this particular case, shall remain nameless (but you know who you are, and thank you!) was kind enough to tip me off about a great team he met on the east coast but one that he couldn’t […]
    - 38 days ago 3 Nov 17, 2:14pm -
  • Podcast: The Backstory Of Raising Haystack IV (The Full Ratchet)
    As my Podcast 2017 Tour continues, Nick Moran from Chicago’s The Full Ratchet was kind enough to have me on his show again a second time. Two years ago, I was a guest on The Full Ratchet discussing the intricacies of how seed-stage companies gradua…
    - 39 days ago 2 Nov 17, 5:39pm -
  • My Second 20 Minute VC Appearance: The Mechanics Of Raising A First Institutional VC Fund
    About a year and a half ago, I had my first experience on as a guest on Harry Stebbings‘ famous podcast, The 20 Minute VC. In that older episode, we mainly covered the importance of individual and firm branding in today’s ecosystem. Fast-forward…
    - 49 days ago 23 Oct 17, 2:56pm -

Brad Feld

  • !Book: Why We Sleep
    As part of v52 of me, I’ve decided to commit to at least eight hours of sleep a night. I’m doing ok, but need to keep working at it. From my early 20s, until v47, I woke up at 5 am from Monday to Friday. I’d then binge sleep on the weekend, oft…
    - 18 hours ago 11 Dec 17, 4:18am -
  • Welcoming Bobby Schnabel Back to CU Boulder
    Bobby Schnabel has returned to CU Boulder as the College of Engineering and Applied Science faculty director for entrepreneurial leadership, external chair of computer science, and campus thought-leader on computing. I first met and worked with Bo…
    - 4 days ago 7 Dec 17, 6:19pm -
  • @bfeld v52.0
    I turned 52 on Friday. Last year, when I turned 51, I wrote a post titled @bfeld v51.0 where I talked about several things that I wanted to change in v51 of me. This year, I enhanced my annual tradition of birthday reflection by reviewing my previou…
    - 9 days ago 3 Dec 17, 4:30am -
  • Apple Platform Layer Bugs
    The word “platform” used to mean something in the technology industry. Like many other words, it has been applied to so many different things to almost be meaningless. Yesterday, when I started seeing stuff about the MacOS High Sierra blank root…
    - 12 days ago 29 Nov 17, 3:30pm -
  • Ozymandias – A Poem on My Indifference to Legacy
    I’ve spoken openly about how I don’t care about the idea of legacy. When pressed, I’ve struggled to describe the reason why I don’t care. My long-time friend and first business partner Dave Jilk sent me the following Percy Bysshe Shelley poem…
    - 13 days ago 28 Nov 17, 1:57pm -

Om Malik

  • Shadows
    Photo 07/30: iPhoneX, ISO 20, f4, 1/200th of a second. 
    - 3 days ago 8 Dec 17, 2:21pm -
  • Selfie
    Photo 06/30: iPhoneX  Portrait mode, ISO 25, f2.4, 1/30th of a second. 
    - 4 days ago 7 Dec 17, 1:53pm -
  • Some thoughts on the Blog Post Bribe Scandal
    The Outline, an often forgotten but exciting web publication, exposed a widespread practice at publications such as Mashable, Entrepreneur, Business Insider, Huffington Post and Forbes, wherein freelance writers were taking payments in exchange for f…
    - 5 days ago 6 Dec 17, 4:41pm -
  • You are stressing me out…. Man!
    Right there on the corner of Brannan and Fourth Streets, there is a billboard advertising some marijuana brand, saying “Hello marijuana, goodbye stress.” It got me thinking about stress and what is that is making people stressed out? Also, what d…
    - 6 days ago 5 Dec 17, 7:59pm -
  • Will AI match randomness of a human mind?
    The other Sunday, I was sitting in Sightglass, chatting with a friend and having coffee. It is what I usually do on the weekend, talk to friends in real life. He stepped away for a few minutes and all I heard between the strains of rock music, the co…
    - 7 days ago 4 Dec 17, 1:30pm -


  • Operating Systems For Living Medicines
    We've Moved! Update your Reader Now.This feed has moved to: https://lifescivc.com/feed/Update your reader now with this changed subscription address to get your latest updates from us.
    - 5 days ago 6 Dec 17, 11:19am -
  • In Search Of Novelty: 2017’s New FDA Drug Approvals
    We've Moved! Update your Reader Now.This feed has moved to: https://lifescivc.com/feed/Update your reader now with this changed subscription address to get your latest updates from us.
    - 11 days ago 30 Nov 17, 1:35pm -
  • Brexit – Own Goal Or Overhead Kick?
    We've Moved! Update your Reader Now.This feed has moved to: https://lifescivc.com/feed/Update your reader now with this changed subscription address to get your latest updates from us.
    - 14 days ago 27 Nov 17, 11:18am -
  • Painful Truth: Successful Failure Of A Biotech Startup
    We've Moved! Update your Reader Now.This feed has moved to: https://lifescivc.com/feed/Update your reader now with this changed subscription address to get your latest updates from us.
    - 24 days ago 17 Nov 17, 11:56am -
  • Living Medicines With Curative Intent: Small N’s Go Viral
    We've Moved! Update your Reader Now.This feed has moved to: https://lifescivc.com/feed/Update your reader now with this changed subscription address to get your latest updates from us.
    - 34 days ago 7 Nov 17, 12:10pm -


  • !AlphaZero Chess: Computers Will Think Differently from Humans, Letting them Outperform Us (on Many Tasks)
    Planes fly differently from birds. Cars move differently from horses. And computers think differently from humans. That had always been my assumption but if you needed more proof, Google’s AlphaZero program, which had previously shown novel ways of…
    - 11 hours ago 11 Dec 17, 12:04pm -
  • The Quest for a Stable Coin
    One of the objections against crypto currencies has been their volatility. Bitcoin for instance just rose by about 60% over 2 days only to then fall by about 15% in a matter of hours. Steam just ended bitcoin support citing volatility. This has led a…
    - 3 days ago 8 Dec 17, 6:54pm -
  • Uncertainty Wednesday: Suppressed Volatility
    Last Uncertainty Wednesday provided a recap on our adventures with sample means and what those implied about the difficulties of inference. Now we will look at another equally fascinating complication: inferring volatility. As the title of this initi…
    - 5 days ago 6 Dec 17, 1:29pm -
  • What Does it Mean to Be Human?
    [This is a talk I was going to give at Slush but had to change my travel plans.] A 12 minute talk should be plenty to address this simple question. Just kidding. This is one of the profound questions that humanity has grappled with for a long time. H…
    - 6 days ago 5 Dec 17, 10:59pm -
  • Uncertainty Wednesday: Recap on Sample Behavior (Inference)
    The last few weeks in Uncertainty Wednesday, with the exception of my net neutrality post, we have been looking at the relationship between sample data and distributions. Today is a bit of a recap so that we know where we are. One of the reasons for…
    - 12 days ago 29 Nov 17, 9:33pm -

Hunter Walk

  • You Can’t Bullshit a Good VC, But You Can MAKE THEM BELIEVE
    It’s the season of giving, so when my friend Nathan Bashaw asked for follow-up on my last post, well, I cracked open WordPress to deliver! Nathan wanted my POV on the difference between bullshitting to investors versus telling a BIG VISION CRAZY ST…
    - 2 days ago 10 Dec 17, 2:19am -
  • To Raise a Venture Round These Days, You Need To Be a Little Crazy
    None of our portfolio companies seeking additional dollars in 2017 had a “standard” venture fundraise. You know, the one where you advise the company “plan to take 2-3 months to get one or more term sheets and then another month to close.” Ze…
    - 4 days ago 8 Dec 17, 1:21am -
  • Internet Content Moderation 101
    Since Facebook, Twitter and YouTube have all been vocal (to various degrees) about staffing up the human element of their content moderation teams, here are a few things to understand about how these systems typically work. Most of this is based on m…
    - 6 days ago 5 Dec 17, 9:03pm -
  • For VCs, “What Could Go Right” Is More Important Than “What Could Go Wrong”
    You ever notice how when someone leads off by saying, “Now, I don’t mean to overgeneralize but…” they almost always are overgeneralizing? Now, I don’t mean to overgeneralize but I want to tell you about something that reporters and pundits…
    - 12 days ago 30 Nov 17, 2:00am -
  • Five Posts I Would Have Written If Someone Else Hadn’t
    Flying back to San Francisco, spending some time in my Pocket since I rarely read anything when it’s actually published. Here are a bunch of posts that I enjoyed, most VC or startup related, so if you don’t care about that stuff, skip this. The A…
    - 16 days ago 25 Nov 17, 6:27pm -